This course is designed to explore the current state of the molecular basis of complex genetic variation in humans and to use this information in different research areas applying new methodologies. The course program consists of lectures and practical sessions that are geared toward moving from GWAS data to functional studies. Data from genome-wide association studies will explore, starting from experimental design, through data analysis of genetic control of traits and their impact of functional information on variations.
The course will use a combination of lectures and demonstrations with a heavy emphasis on hands-on data analysis, which requires the active participation of students. The focus will be on making maximum interaction with teachers and the creation of useful contacts with the other participants.
The workshops will use programming languages, applicable tools and web-based portals to analyze high-throughput genotyping and sequencing datasets covering the different topics of the course (low pass and deep coverage whole genome DNA, statistical methods for imputation, analysis of exomes, quantitative and qualitative analysis of the transcriptome, epigenome and other related issues).
Who should attend
This summer school is intended for advanced pre-doctoral students, post-doctoral researchers from Biological and Health Sciences and other different backgrounds (including bioinformatics and mathematics) that wish to learn more about or move into the complex genomics field.
Attendees should have as prerequisite background knowledge on most of the topics presented during the course.
Skills and abilities to work in a Linux system are a prerequisite for attending the workshops.
Good spoken and written English is essential for all lectures and workshops.
Participants are asked to bring their laptop computers.
The course is funded by the Regional Sardinian government and will be free of charge for all attendees.